Dr. Kaplan | Medical Director, New York Neurology Institute, is a board-certified neurologist and pain management specialist with extensive expertise in disorders of the brain, nerves, and pain systems.
At NYNA he provides comprehensive, science-driven care for patients with a full range of neurological disorders, including all headache types, chronic neck pain, oromandibular (jaw) pain, facial pain syndromes, dizziness, imbalance, peripheral neuropathy and nerve injury, neuropathic pain syndromes, dysautonomia (including POTS), small fiber neuropathy, chronic fatigue syndrome, and post-infectious neurological conditions, such as Long-COVID, tremor, dystonia and other movement disorders, neurocognitive disorders, dementia and Alzheimer’s disease.
Dr. Kaplan has particular interest in the neurological complications of hypermobility spectrum disorders and hypermobile Ehlers-Danlos syndrome (hEDS). His diagnostic approach combines advanced neurophysiological testing, imaging, and autonomic function assessment to uncover the neurological underpinnings of pain, fatigue, and autonomic dysfunction—enabling more targeted and effective management for these complex conditions.
Dr. Kaplan provides patient-centered care that emphasizes collaboration across disciplines, partnering with experts in internal medicine, surgery, and functional medicine. He treats patients with complex neurological and chronic conditions involving multiple body systems, integrating advanced diagnostics with compassionate, whole-person care. By recognizing the value of both traditional and integrative approaches, Dr. Kaplan aims to improve long-term health outcomes and enhance quality of life.
As a key member of the NYNA Headache and Pain Treatment Center, Dr. Kaplan provides expert diagnosis and comprehensive multimodal treatment for migraine and all other headache types, facial pain, trigeminal neuralgia, TMJ disorders, and post-traumatic pain syndromes.
His extensive experience in chemodenervation therapies ( e.g. Botox®) for chronic migraine, dystonia, hemifacial spasm, spasticity, and neuropathic pain was honed during his tenure in the Movement Disorders Division at Columbia University Medical Center. There, he developed tailored Botox treatment paradigms and refined ultrasound- and EMG-guided injection techniques that continue to shape his precise, patient-specific approach to pain and neuromuscular care.
Deeply committed to his patients, Dr. Kaplan believes that effective care for complex disorders requires not only scientific expertise but also compassion, trust, and long-term partnership. His practice reflects a holistic approach where advanced medicine and meaningful connection work together to improve quality of life.
Dr. Kaplan serves as the Medical Director of the New York Neurology Institute and as Principal Investigator on multiple ongoing clinical trials in Alzheimer’s disease, migraine, epilepsy, Parkinson’s disease, and other movement disorders. He has published peer-reviewed research, presented at national and international neurology conferences.
Kaplan A, Brannagan TH 3rd. Evaluation of patients with refractory chronic inflammatory demyelinating polyneuropathy. Muscle Nerve. 2016 Jul 27
Kaplan A*, Spiller KJ*, Towne C, Kanning KC, Choe GT, Geber A, Akay T, Aebischer P, Henderson CE. Neuronal matrix metalloproteinase-9 is a determinant of selective neurodegeneration. Neuron 2014 Jan 22;81(2):333-48.*co-first authors
Kanning KC, Kaplan A, Henderson CE. Motor neuron diversity in development and disease. Annu Rev Neurosci. 2010;33:409-40
Auerbach MR, Brown KR, Kaplan A, de Las Nueces D, Singh IR. A small loop in the capsid protein of Moloney murine leukemia virus controls assembly of spherical cores. J Virol. 2006 Mar;80(6):2884-93.
Auerbach MR, Shu C, Kaplan A, Singh IR. Functional characterization of a portion of the Moloney murine leukemia virus gag gene by genetic footprinting. Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11678-83.
Kanning KC, Li H, Nikulina E, Hou J, Yang WS, Kaplan A, Bermingham JR, Lamas NJ, Amoroso MW, Wichterle H. Making motor axons grow. International Journal of Developmental Neuroscience 30 (8), 613-614
Clinical Characteristics and Treatment Response of Patients with Chronic Inflammatory Demyelinating Neuropathy Refractory to Standard Therapy. Herbert and Rhoda Cohen Neurology Residents’ Research Day. May 2015.
Clinical Characteristics and Treatment Response of Patients with Chronic Inflammatory Demyelinating Neuropathy Refractory to Standard Therapy. American Academy of Neurology annual meeting. April 2015. Poster Presentation.
Neuronal matrix metalloproteinase-9 is a determinant of selective neurodegeneration. Poster presentation. Herbert and Rhoda Cohen Neurology Residents’ Research Day. May 2014. MMP-9 is a marker of motor neurons vulnerable in ALS. Poster presentation. Student research day at the College of Physicians and Surgeons. April 2011.
Mechanisms of ALS resistance in motor neurons of oculomotor and Onuf’s nuclei. Platform presentation. 21st international symposium on ALS/MND. December 2010.
Mechanisms of motor neuron degeneration in ALS. Poster presentation. Integrated Program in cellular, molecular, and biophysical studies departmental retreat. July 2010.
Disease-resistance mechanisms in ALS and SMA. Platform presentation. Motor Neuron Center at Columbia University new laboratories opening ceremony scientic session. May 2010.
Mechanisms of ALS resistance in motor neurons of oculomotor and Onuf’s nuclei. Poster presentation. Neurobiology and behavior departmental retreat. September 2009.
Mechanisms of motor neuron degeneration in ALS. Poster presentation. Integrated program in cellular, molecular, and biophysical studies departmental retreat. July 2008
Profile Details
Board Certifications
Pain Medicine, American Board of Pain Medicine
Clinical Neurophysiology, American Board of Psychiatry and Neurology
Neurology, American Board of Psychiatry and Neurology
Specialties:
Clinical neurophysiology
Migraine/headache (hemicrania continua, cluster headaches, SUNCT)
Botox therapy for chronic migraines, TMJ, cervical dystonia, orofacial dystonia, hemifacial spasm, spasticity, neuropathic pain, sialorrhea
Dysautonomia/POTS
Hypermobility syndromes/hEDS
Long-COVID-19 Syndrome
NCV/EMG testing for nerve injury, neuropathy neuromuscular dysfunction
Skin biopsy
Facial/oral pain
Neuropathic pain
Carpal Tunnel Syndrome
Peripheral neuropathy, Chronic Inflammatory Demyelinating Polyneuropathy, Small fiber neuropathy
Alzheimer's Disease
Dementia
Mild cognitive impairment
Dizziness
Imbalance
